Cross-linked Gels of Hyaluronic Acid.

Preparation and investigation of cross-linked hyaluronic acid nanoparticle systems

Rheological properties of cross-linked hyaluronic acid dermal fillers.

AIM Ha based dermal fillers in recent years aroused big interest in the area of cosmetic surgery for the rejuvenation of the dermis. There is not a ideal dermal filler (DF) for all applications and in commerce there are many types of DF that differ for their chemical-physical properties. So the aim of this paper is to correlate the rheological and physical properties of different DF to their cl...

Brillouin scattering from cross-linked gels

In this letter we report Brillouin scattering measurements on methyl-methacrylate (MMA) gels crosslinked with varying amounts of ethylene-dimethacrylate (EDMA). We find that the k dependence of the phase velocity changes on increasing the cross-link content. For higher concentrations of crosslink we observe maxima and minima in the k dependence of the phase velocity. We associate these minima a...

Interaction between hyaluronic acid and serum dispersed in collagen gels.

A high degree of viscosity is the most striking physical attribute of normal synovial fluid. Although its direct relationship to the lubrication of joints remains uncertain, this viscosity still reflects physiologically important properties of hyaluronic acid. The anomalous viscosity which is a particular feature of hyaluronic acid in synovial fluid depends not only on the concentration and pol...

Mechanical and biocompatible characterization of a cross-linked collagen-hyaluronic acid wound dressing

Collagen scaffolds have been widely employed as a dermal equivalent to induce fibroblast infiltrations and dermal regeneration in the treatment of chronic wounds and diabetic foot ulcers. Cross-linking methods have been developed to address the disadvantages of the rapid degradation associated with collagen-based scaffolds. To eliminate the potential drawbacks associated with glutaraldehyde cro...